Monday, August 31, 2009

Coleman Research Group’s Healthcare department highlights Light Shed On Cause Of Down Syndrome and Virus Enzymes Could Promote Human, Animal Health

Coleman Research Group’s Healthcare Team facilitates consultations between our clients (institutional investors) and leading healthcare professionals on a wide variety of topics including pharmaceuticals, biotechnology, clinical research, medical devices, healthcare providers, insurance, and regulatory issues.

Our Healthcare network spans technology industries across the globe and includes doctors, researchers, scientists, healthcare executives, consultants, and former regulatory officials.

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Light Shed On Cause Of Down Syndrome And Other Genetic Disorders

ScienceDaily (Aug. 31, 2009) — Scientists have a better understanding of what causes an abnormal number of chromosomes in offspring, a condition called aneuploidy that encompasses the most common genetic disorders in humans, such as Down syndrome, and is a leading cause of pregnancy loss.

To pinpoint what goes awry in these cases, researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory and the University of Tennessee, Knoxville studied mice. They found that if a mother’s egg cell has a mutation in just one copy of a gene, called Bub1, then she is more likely to have fewer offspring that survive to birth.

Ordinarily, both copies of a gene in a chromosome must carry the same mutation in order for an organism to be adversely effected.

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Virus Enzymes Could Promote Human, Animal Health

ScienceDaily (Aug. 31, 2009) — Could viruses be good for you? Scientists with the Agricultural Research Service (ARS) have shown that enzymes from bacteria-infecting viruses known as phages could have beneficial applications for human and animal health.

Phage enzymes called endolysins attack bacteria by breaking down their cell walls. Unlike antibiotics, which tend to have a broad range, endolysins are comparatively specific, targeting unique bonds in the cell walls of their hosts. This is significant because it means non-target bacteria could be less likely to develop resistance to endolysins.

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